Figure 3

Determining Side of Seizure Unset Using OI and PI. Regions in blue indicate a significant (Mann-Whitney U Test, two-tailed, p < 0.05) difference between the distributions of normalised standard deviations of a group (Left Focal (n = 23), Right Focal (n = 20) or IGE (n = 25)) and the control cohort (n = 38) for that specific region. Regions in red indicate the strongest significant difference of all regions in the network. For the regions in black the outcome of the Mann-Whitney U test was to accept the hypothesis that the distributions are similar for that region. We found no regions for the generalised epilepsies that were significantly different to the healthy controls, whereas for focal epilepsies the regions with highest values of normalised standard deviations of the OI and PI were associated with the affected hemisphere.