Figure 5 | Scientific Reports

Figure 5

From: Identification of tipifarnib sensitivity biomarkers in T-cell acute lymphoblastic leukemia and T-cell lymphoma

Figure 5

DE genes and pathways commonly regulated by tipifarnib in JURKAT (pink), RPMI-8402 (yellow) and SU-DHL-1 (blue) cell lines. (a) 24 genes commonly downregulated (left) and upregulated (right) with tipifarnib, with adjusted values of p < 0.05. Bars show log-fold change. (b) Pathways downregulated by tipifarnib. Normalized enrichment score (p < 0.05; FDR < 5%). Bars show log-fold change.

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