Figure 1
From: Genome wide association study of 40 clinical measurements in eight dog breeds
Results of a meta-analysis for ALT. (a) Manhattan plot of a meta-analysis (CanFam 3.1). (b) Local association profile for each breed covering 36–40 Mb of chromosome 13. The red line indicates p = 0.05. (c) Fig. 1c zoomed to the position 36–40 Mb of chromosome 13 in (a). Each dot shows the p value of the meta-analysis. We searched for the highest association of each breed separately. The three breeds with black font shared the same association signal, although lead SNPs were different and had high linkage disequilibrium (r2 > 0.973) with the lead SNP of the meta-analysis (BICF2P496164). Finnish Lapphunds with red color had an independent association signal, and Newfoundlands had two independent association signals colored in green and blue, because BICF2P496164 did not have high linkage disequilibrium with their lead SNPs in each breed.
