Table 3 Genes (raw estimated fold change ≥2, FDR corrected P < 0.05) integrating the oxidative phosphorylation canonical pathway generated by Ingenuity Pathway Analysis (IPA) in comparisons of the early and middle stages and late and middle stages.
Gene Symbol | Fold change | P-value | Gene Name | Location | Type | ||
|---|---|---|---|---|---|---|---|
Middle vs. Early | Late vs. Middle | Middle vs. Early | Late vs. Middle | ||||
ATP5F1C | −3.39 | 2.16 | 2.38.E-04 | 3.86.E-05 | ATP synthase F1 subunit gamma | Cytoplasm | Transporter |
ATP5F1B | −2.16 | 7.60.E-04 | ATP synthase F1 subunit beta | Cytoplasm | Transporter | ||
ATP5PO | 2.05 | 4.86.E-05 | ATP synthase peripheral stalk subunit OSCP | Cytoplasm | Transporter | ||
ATPAF1 | −3.40 | 3.94 | 4.75.E-04 | 6.83.E-06 | ATP synthase mitochondrial F1 complex assembly factor 1 | Cytoplasm | Other |
COX11 | 2.33 | 2.69.E-04 | cytochrome c oxidase copper chaperone COX11 | Cytoplasm | Enzyme | ||
NDUFA6 | −4.22 | 2.33.E-08 | NADH:ubiquinone oxidoreductase subunit A6 | Cytoplasm | Enzyme | ||
NDUFA9 | −2.06 | 4.26.E-04 | NADH:ubiquinone oxidoreductase subunit A9 | Cytoplasm | Enzyme | ||
NDUFAB1 | 2.02 | 3.42.E-04 | NADH:ubiquinone oxidoreductase subunit AB1 | Cytoplasm | Enzyme | ||
NDUFS1 | −3.20 | 3.07 | 2.89.E-05 | 1.95.E-08 | NADH:ubiquinone oxidoreductase core subunit S1 | Cytoplasm | Enzyme |
NDUFS6 | −2.22 | 2.40.E-03 | NADH:ubiquinone oxidoreductase subunit S6 | Cytoplasm | Enzyme | ||
NDUFV3 | −2.06 | 2.18 | 7.68.E-03 | 3.07.E-03 | NADH:ubiquinone oxidoreductase subunit V3 | Cytoplasm | Enzyme |
SDHA | −7.32 | 7.18 | 2.73.E-06 | 2.14.E-10 | succinate dehydrogenase complex flavoprotein subunit A | Cytoplasm | Enzyme |
SDHB | −3.18 | 3.57 | 4.64.E-04 | 9.90.E-06 | succinate dehydrogenase complex flavoprotein subunit B | Cytoplasm | Enzyme |
SDHC | −3.42 | 2.78 | 3.90.E-05 | 1.27.E-07 | succinate dehydrogenase complex flavoprotein subunit C | Cytoplasm | Enzyme |
UQCRC1 | −4.71 | 3.57 | 1.78.E-04 | 1.42.E-05 | ubiquinol-cytochrome c reductase core protein 1 | Cytoplasm | Enzyme |
UQCRQ | −2.25 | 1.86.E-05 | ubiquinol-cytochrome c reductase complex III subunit VII | Cytoplasm | Enzyme | ||