Table 1 Demographics of participants.
|  | CS (n = 76) | FEP (n = 78) | HC (n = 75) | F/t/χ2 | P |
|---|---|---|---|---|---|
Age (years) | 37.49 ± 11.14 | 26.03 ± 6.45 | 37.51 ± 12.3 | 32.269 | 0.000 |
Sex (Males, %) | 37/39 | 40/38 | 42/33 | 0.831 | 0.660 |
Education (years) | 9.67 ± 3.84 | 10.01 ± 3.18 | 12.51 ± 3.85 | 13.735 | 0.001 |
Smoking (yes,%) | 27/49 | 28/50 | 33/42 | 1.466 | 0.481 |
Age of onset (years) | 23.99 ± 8.46 | 24.29 ± 5.27 |  | 0.270 | 0.787 |
Duration of illness (years) | 13.50 ± 9.84 | 1.73 ± 2.20 |  | 10.182 | 0.000 |
family history of mental illness(yes,%) | 16(21.05) | 17(21.79) | Â | 0.013 | 0.911 |
PANSS Total Score | 78.88 ± 6.52 | 79.09 ± 5.04 |  | 0.221 | 0.825 |
Positive subscore | 23.91 ± 5.82 | 24.24 ± 8.47 |  | 0.287 | 0.774 |
Negative subscore | 24.07 ± 6.48 | 21.42 ± 8.03 |  | −2.251 | 0.026 |
General subscore | 30.91 ± 6.61 | 33.42 ± 3.59 |  | 2.924 | 0.004 |
Cognitive subscore | 12.12 ± 2.82 | 11.37 ± 3.77 |  | −1.393 | 0.166 |
Atypical antipsychotics alone (n,%) | |||||
Aripiprazole | 8(10.53) | Â | Â | Â | Â |
Amisulpride | 7(9.21) | Â | Â | Â | Â |
Clozapine | 5(6.58) | Â | Â | Â | Â |
Olanzapine | 9(11.84) | Â | Â | Â | Â |
Risperidone | 11(14.47) | Â | Â | Â | Â |
Quetiapine | 10(13.16) | Â | Â | Â | Â |
Ziprasidone | 7(9.21) | Â | Â | Â | Â |
A combination of antipsychotics (n,%) | |||||
Clozapine-risperidone combination | 7(9.21) | Â | Â | Â | Â |
Clozapine-aripiprazole combination | 6(7.89) | Â | Â | Â | Â |
Clozapine-quetiapine combination | 6(7.89) | Â | Â | Â | Â |
chlorpromazine equivalent (mg/day)  | 492.87 ± 203.89 |  |  |  |  |