Table 2 Binding parameters of compound 31 upon CT-DNA and BSA interactions.

From: Synthesis, cytotoxicity, pharmacokinetic profile, binding with DNA and BSA of new imidazo[1,2-a]pyrazine-benzo[d]imidazol-5-yl hybrids

Biomolecules

KSV (×104) (M−1)

Kq (×1012) (M−1s−1)

aR

Kbin (×104 M−1)

n

bR

CT-DNA

0.93

0.93

0.9942

9.58

1.21

0.9630

BSA

10.40

10.40

0.9825

4.70

0.92

0.9797

  1. aR (KSV and Kq) and bR (Kbin and n) are the correlation coefficients.
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