Table 3 Initial high-frequency oscillatory ventilation settings.
Variable | Term and late-preterm infants with acute respiratory failure | Rescue therapy for premature infants | Elective use of HFOV | Air leak | Patients with secondary pulmonary hypertension |
|---|---|---|---|---|---|
Days of starting HFOV, median (IQR) | 1.0 (1.0–2.0) | 1.0 (1.0–4.0) | 1.0 (1.0–3.0) | 1.0 (1.0–2.0) | 56.0 (32.0–100.5) |
DeltaP, cm H2O | 30.0 (22.5–36.5) | 100.0 (77.5–100) | 100 (100–100) | 51.5 (26.0–100.0) | 40.0 (31.0–85.0) |
Frequency, Hz | 12.0 (11.0–13.0) | 12.0 (11.0–13.0) | 13.0 (11.0–14.0) | 13.0 (11.0–14.0) | 12.0 (10.5–13.0) |
FiO2 | 100 (80–100) | 90 (80–100) | 45.0 (40.0–56.3) | 77.5 (51.5–100) | 100.0 (75.0–100.0) |
Oxygenation index | 25.0 (17.5–39.0) | 15.0 (10.0–28.0) | 6.0 (4.0–9.0) | 15.0 (10.0–30.0) | 29.0 (22.0–46.8) |
AaDO2 | 528.0 (391.5–590.0) | 393.0 (250.0–565.0) | 167.0 (111.3–234.0) | 367.0 (211–579) | 556.0 (378.0–595.5) |
Mean airway pressure (cmH2O) | 15.0 (13.0–17.0) | 11.0 (10.0–13.0) | 10.0 (8.0–11.0) | 11.0 (10.0–14.0) | 16.0 (13.0–20.0) |
PH* | 7.23 (7.14–7.30) | 7.24 (7.11–7.35) | 7.32 (7.26–7.38) | 7.26 (7.13–7.36) | 7.35 (7.27–7.44) |
PaO2 | 51.6 (36.0–70.9) | 52.9 (36.5–79.7) | 71.9 (52.9–98.3) | 56.9 (38.9–80.1) | 46.7 (37.3–59.3) |
PaCO2 | 52.9 (41.8–67.3) | 52.0 (42.3–66.8) | 44.2 (37.2–51.1) | 54.9 (43.3–63.9) | 52.0 (44.3–70.0) |