Table 4 Treatment outcomes of neonates treated by high-frequency oscillatory ventilation (HFOV).

From: Use of high frequency oscillatory ventilator in neonates with respiratory failure: the clinical practice in Taiwan and early multimodal outcome prediction

Treatment outcomes

Term and late-preterm infants with acute respiratory failure

Rescue therapy for premature infants

Elective use of HFOV

Air leak

Patients with secondary pulmonary hypertension

Good response

94 (58.4)

314 (61.9)

276 (90.2)

61 (62.2)

10 (18.9)

Partial response

28 (17.4)

71 (14.0)

15 (4.9)

13 (13.3)

16 (30.2)

Partial response and then failure

7 (4.3)

36 (7.1)

9 (2.9)

5 (5.1)

7 (13.2)

Failure

32 (19.9)

86 (17.0)

6 (2.0)

19 (19.4)

20 (37.7)

Progress to BPD*

17/154 (11.0)

252/443 (56.9)

191/276 (69.2)

32/95 (33.7)

Duration of HFOV (days)

4.0 (2.0–6.0)

5.0 (3.0–19.0)

8.0 (3.0–27.0)

4.5 (3.0–8.0)

9.0 (3.5–28.5)

Duration of intubation (days)

5.0 (2.0–10.0)

23.0 (4.0–50.0)

32.0 (10.8–54.3)

7.0 (3.5–39.0)

57.0 (32.5–91.3)

Duration of mechanical ventilation (days)

9.0 (6.0–17.0)

40.0 (12.0–73.0)

53.0 (24.0–75.3)

10.0 (5.0–54.0)

76.0 (43.5–132.0)

30-day mortality

40 (24.8)

154 (30.4)

35 (11.4)

24 (24.5)

31 (58.5)

  1. Data are presented as the number (percentage), while duration of HFOV, intubation and mechanical ventilation are expressed as median (interquartile range).
  2. BPD: bronchopulmonary dysplasia, defined based on the diagnostic criteria of the American Thoracic Society21.
  3. *Only considers the patients who received HFOV during the first two weeks of life and survived for more than 4 weeks.