Figure 3
Hyperplastic and neoplastic lesions in quartz-treated groups. (a-d) Inflammatory change (group 52w-quartz); (e-h), hyperplasia (group 96w-quartz); (i-l), adenoma (group 96w-quartz); (m-p) adenocarcinoma (group 96w-quartz); (q,r), papilloma, bronchiole (group 96w-quartz); (a,e,i,m,q), low magnification; (b,f,j,n,r) high magnification; (c,d,g,h,k,l,o,p), immunohistochemical assessments; (c,g,k,o), SP-C; (d,h,l,p), napsinA; (s), incidences of hyperplastic and neoplastic lesions; (t), numbers of hyperplastic and neoplastic lesions per rat. *, **Significant differences compared with the saline i.t. group (P < 0.05, <0.01, respectively). Data presented are means ± SD.
