Figure 8 | Scientific Reports

Figure 8

From: Store-operated Ca2+ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration

Figure 8

Migration of STIM1/2- deficient primary murine lung fibroblasts (pmLF) and control cells (a,b). (a) Images from a representative migration assay with STIM1/2- deficient pmLF compared to Wt cells infected with recombinant lentiviruses expressing Cre recombinase (Wt Cre) after removing inserts. (b) Summary of remaining gap values normalized to initial values quantified in migration assays of STIM1/2- deficient pmLF compared to Wt cells infected with recombinant lentiviruses expressing Cre recombinase (Wt Cre) after removing inserts at 0, 4, 8, 12 and 24 h. Data represent means ± SEM from 3 independent cell preparations of 5 mice each. Asterisks mark significant differences (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001) between ratios of STIM1/2-deficient cells compared to control cells.

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