Table 1 General characteristics about sepsis in the study population.

From: The Influence of the Variation in Sepsis Rate between Neonatal Intensive Care Units on Neonatal Outcomes in Very-Low-Birth-Weight Infants

 

Propensity score matching

Unmatched data set (N = 7,493)

Matched data set (N = 2,538)

Low sepsis group (N = 1,873)

Intermediate sepsis group (N = 3,631)

High sepsis group (N = 1,989)

P-value

Low sepsis group (N = 846)

Intermediate sepsis group (N = 846)

High sepsis group (N = 846)

P-value

Sepsis incidence density (cases per 1,000 person-day)

1.17

3.17

8.88

<0.001*,**,†

1.27

2.99

9.04

<0.001*,**,†

Sepsis, total, number (%)

125 (6.7%)

656 (16.9%)

721 (36.2%)

<0.001*,**,†

65 (7.7%)

137 (16.2%)

320 (37.8%)

<0.001*,**,†

Early-onset

26 (1.4%)

52 (1.4%)

52 (2.6%)

<0.001*,**,†

19 (2.2%)

13 (1.5%)

21 (2.5%)

<0.001*,**,†

Late-onset

99 (5.3%)

563 (15.5%)

669 (33.6%)

46 (5.4%)

124 (14.7%)

299 (35.3%)

Sepsis, bacterial, number (%)

114 (6.1%)

580 (16.0%)

699 (35.1%)

<0.001*,**,†

60 (7.1%)

129 (15.2%)

314 (37.1%)

<0.001*,**,†

Sepsis, Fungal, number (%)

11 (0.6%)

63 (1.7%)

65 (3.3%)

<0.001*,**,†

5 (0.6%)

10 (1.2%)

23 (2.7%)

0.001**

Sepsis, multiple, number (%)

18 (1.0%)

112 (3.1%)

169 (8.5%)

<0.001*,**,†

9 (1.1%)

28 (3.3%)

74 (8.7%)

<0.001*,**,†

First postnatal day of sepsis(days)

14 [5,27]

15 [7,28]

15 [8,27]

0.172

13 [0, 23]

14 [7,27]

16 [9,29]

0.029**

  1. Propensity score matching via gestational age, gender, small for gestational age, multiple pregnancies, cesarean section, hypertensive disorders of pregnancy, histologic chorioamnionitis, oligohydramnios, complete course of antenatal corticosteroid use, delivery room resuscitation, and 5 minute Apgar score.
  2. Kruskal-Wallis test or chi-square test in both propensity score unmatched population and propensity score matched population.
  3. *P < 0.05 between low sepsis group and intermediate sepsis group.
  4. **P < 0.05 between low sepsis group and high sepsis group.
  5. P < 0.05 between intermediate sepsis group and high sepsis group.