Table 1 Patient characteristics and therapeutic outcomes of endoscopic submucosal dissection for undifferentiated-type gastric cancer (265 patients, 277 lesions).

From: Undifferentiated-type predominant mixed-type early gastric cancer is a significant risk factor for requiring additional surgeries after endoscopic submucosal dissection

Characteristic

N (%)

Age, years

58 (48–67)30–86

Sex, male/female

154/111 (58.1/41.9)

Location

   Upper third

29 (10.5)

   Middle third

181 (65.3)

   Lower third

67 (24.2)

Macroscopic type

   Flat, depressed

271 (97.8)

   Others(Complex, Elevated)

6 (2.2)

Pre-treatment histology based on biopsy findings

   P-UDT

270 (97.5)

   M-UDT

7 (2.5)

Therapeutic outcomes

Median tumour diameter, mm

10 (6–15) 1–40

   ≥20 mm

19 (6.9)

Invasion depth

   Intramucosal

252 (91.0)

   Submucosa

25 (9.0)

Presence of lymphovascular invasion

   Lymphatic invasion

4 (1.4)

   Vascular invasion

1 (0.3)

Positive vertical margin

4 (1.4)

Positive horizontal margin

7 (2.5)

Presence of ulcerative findings

14 (5.0)

En bloc resection

276 (99.6)

Post-treatment histological type

   P-UDT

258 (93.1)

   M-UDT

19 (6.9)

eCURA B

229 (82.7)

  1. Data are presented as number (%), except for age and tumour diameter, which are expressed as median (interquartile range) [range].
  2. M-UDT, undifferentiated type predominant mixed type; P-UDT, pure undifferentiated type.
  3. eCURA B was defined in accordance with the Japanese guidelines for intramucosal undifferentiated lesions measuring ≤20 mm in diameter, lesions without ulcerative findings, lesions with negative horizontal margins, lesions with negative vertical margins, and lesions without lymphovascular invasion6. eCURA B is refer to the curability not requiring additional surgeries after ESD.
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