Table 1 Baseline characteristics of participants.

n

25

25

Age (years)

52 ± 13 (27–78)

51 ± 13 (27–76)

0,80^#

Male sex (total number)

10 (40)

10 (40)

1,000^†

BMI (kg/m²)

28,2±5,3 (18,9–42,3)

27,0±5,0 (19,8–38,7)

0,45^#

Weight (kg)

81,4±17,8 (54–119)

78,8±18.2 (49,3–117)

0,73^#

Height (cm)

169,6 ± 9,9 (152–193)

170,3 ± 11,5

(148,5–193)

0,83^#

Current smoker

5 (20)

2 (8)

0,417^†

DM family history

13 (52)

11 (44)

0,778^†

Acitretin treatment

14 (56)

0 (0)

<0,001^†

Hypertension treatment

3 (12)

4 (16)

1,000^†

Dyslipidemia treatment

3 (12)

2 (8)

1,000^†

MutatioN related to treatment in DD patients (n = 25)

Pathogenic Mutation

Benign/Unknown/

No Mutation

Mutation Not Analyzed

Acitretin treatment

9

4

1

Isotretinoin treatment

3

0

0

No systemic treatment

4

2

2

Retinoid treatment % of total

75%

67%

33%