Figure 2

Variability in heart rate (HR) and in systolic arterial pressure (SAP) in the time-domain during LPS-induced SI. Standard deviation (SDNN, panel A) and root mean square of the successive differences (RMSSD, panel B) from PI series. Standard deviation (SD) from series (panel C). Control + Sal, Control + LPS, SAD + Sal, and SAD + LPS groups were evaluated 180 min after LPS administration. Results are presented as individual values and mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0,001, ****p < 0.0001 using the one-way ANOVA with Tukey’s post hoc test. Control + Sal (n = 9), Control + LPS (n = 8), SAD + Sal (n = 9), and SAD + LPS (n = 7).