Table 4 Examples of minibeam size (FWHM), PVDR and valley doses evaluated at different depths for treatment plans 3 and 4. The PVDR uncertainties are the standard deviation of the PVDR, as defined in section II.3.

From: First proton minibeam radiation therapy treatment plan evaluation

Depth (mm)

ctc: 4 mm

ctc: 6 mm

Beam size (mm)

PVDR

Valley dose (%)

Beam size (mm)

PVDR

Valley dose (%)

(a) Glioma (field 2)

1

0.7

19.2 ± 1.5

6.2

1.0

29.1 ± 1.9

6.2

10

0.7

17.5 ± 0.6

6.5

1.1

29.1 ± 0.9

6.5

20

0.9

12.8 ± 0.8

7.1

1.2

23.9 ± 1.3

6.9

40

1.2

7.1 ± 0.7

7.5

1.6

16.2 ± 1.4

7.1

60

1.7

3.6 ± 0.2

8.3

2.0

10.8 ± 0.9

12

80

2.1

1.2 ± 0.1

71

3.1

1.5 ± 0.1

61

90

2.2

1.1 ± 0.1

93

3.2

1.4 ± 0.2

84

 

ctc: 4 mm

ctc: 6 mm

Depth (mm)

Beam size (mm)

PVDR

Valley dose (%)

Beam size (mm)

PVDR

Valley dose (%)

(b) Meningioma (field 1)

1

0.7

16.8 ± 2.3

5.2

0.8

44 ± 18

5.1

10

0.7

12.4 ± 1.5

5.8

0.8

35 ± 1

5.3

20

0.8

9.2 ± 0.4

6.1

0.8

22.6 ± 0.7

5.5

40

1.2

5.2 ± 0.2

7.0

1.5

13.6 ± 0.4

5.7

60

2.0

2.4 ± 0.1

9.1

2.6

7.0 ± 0.3

6.5

80

2.3

1.3 ± 0.1

13.5

3.2

2.9 ± 0.1

21

90

2.4

1.1 ± 0.2

73

3.2

1.6 ± 0.2

65