Figure 6
From: Equine penile squamous cell carcinoma: expression of biomarker proteins and EcPV2
Protein expression in EpSCC and NT tissue cores identified EcPV2 positive or negative. Protein expression for Cyclin D1 and c-Myc was evaluated using a TA technique. Genomic DNA was isolated from EpSCC tissue samples and screened for the E1 region of the EcPV2 viral DNA. Tissue array cores were labelled according to their virus infection and expression levels were compared for tumour (EpSCC) and tumour adjacent (NT) tissue cores. Samples that were identified as either hyperplastic or papilloma (Hyp/Pap) were not included in this analysis. Tests of significance are labelled with a bracket (*p < 0.05). Other proteins that were tested, FRA1 and MMP7, showed no significant difference in expression correlated with virus presence.
