Figure 7

Global protein-protein interaction (PPI) networks for differentially expressed genes that altered by REMI mutation involved in nine pathways using STRING database, with COG functions. The nodes represent protein families and the lines represent the existence of the different types of evidence used in predicting the associations. A red line indicates the presence of fusion evidence, a green line shows neighborhood evidence, a blue line for co-occurrence evidence, a purple line indicates experimental evidence, a yellow line for text mining evidence, a light blue line stands for database evidence, and a black line for co-expression evidence.