Table 5 Hazard ratios of all-cause mortality according to KDPI score and the age of KTRs.

From: Impact of Kidney Donor Profile Index Scores on Post-Transplant Clinical Outcomes Between Elderly and Young Recipients, A Multicenter Cohort Study

 

Unadjusted HR (95% C.I.)

P

Adjusted HRa (95% C.I.)

P

P-value for interaction

Low KDPI-young KTR

Reference

 

Reference

 

0.420

Low KDPI-elderly KTR

4.177 (1.304–13.379)

0.016

2.841 (0.314–25.737)

0.353

 

High KDPI-young KTR

2.013 (0.918–4.416)

0.081

1.590 (0.509–4.962)

0.425

 

High KDPI-elderly KTR

2.386 (0.809–7.036)

0.115

2.870 (0.636–12.961)

0.170

 
  1. aAdjusted by DGF, transplant years (1996~2005 vs. 2006~2010 vs. 2011~2017), prior KT, DM of KTRs, HLA mismatch number, high PRA (>50%), eGFR calculated by CKD-EPI equation at 12 months after KT, sex, age of donor, acute rejection, malignancy.
  2. Abbreviations: KDPI, kidney donor profile index; KTR, kidney transplant recipient; HR, hazard ratio; DGF, delayed graft function; KT, kidney transplantation; DM, diabetes mellitus; HLA, human leukocyte antigen; PRA, panel reactive antibody; eGFR, estimated glomerular filtration rate; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration.