Table 2 Characteristics of SEER database and local hospital data by bone metastasis status.

From: Prognosis of prostate cancer and bone metastasis pattern of patients: a SEER-based study and a local hospital based study from China

Character

SEER database

Local hospital data

Bone metastasis 6, 676 (%)

No bone metastasis 170,579 (%)

P value

Bone metastasis 109 (%)

No bone metastasis 1,226 (%)

P value

Age

  

<0.001

  

<0.001

<50

172 (2.58)

5,613 (3.29)

 

2 (1.83)

17 (1.39)

 

50–59

1,088 (16.30)

39,644 (23.24)

 

13 (11.93)

206 (16.80)

 

60–69

2,200 (32.95)

74,105 (43.44)

 

25 (22.94)

565 (46.08)

 

70–79

1,789 (26.80)

41,051 (24.07)

 

34 (31.19)

331 (27.00)

 

>80

1,427 (21.38)

10,166 (5.96)

 

35 (32.11)

107 (8.73)

 

Race

  

<0.001

   

White

4,929 (73.83)

127,873 (74.96)

 

—

—

 

Black

1,297 (19.43)

26,503 (15.46)

 

—

—

 

Asian or Pacific Islander

361 (5.41)

8,269 (4.85)

 

—

—

 

Other

89 (1.33)

7,522 (4.41)

 

—

—

 

Marital statusa

  

<0.001

   

Single

1,185 (17.75)

16,851 (9.88)

 

14 (12.84)

113 (9.22)

<0.001

Married

3,691 (55.29)

106,949 (62.70)

 

53 (48.62)

742 (60.52)

 

Divorced/seprated/window/domestic partner

1,332 (19.95)

18,341 (10.75)

 

34 (31.19)

165 (13.46)

 

Unknown

468 (7.01)

28,438 (16.67)

 

8 (7.34)

206 (16.80)

 

Rural-urban

  

<0.001

   

Urban

5,335 (79.91)

140,326 (82.26)

 

—

—

 

Rural

1341 (20.09)

30,253 (17.74)

 

—

—

 

Composite SESb

  

0.005

—

—

 

≤3

828 (12.40)

18,260 (10.70)

 

—

—

 

4–10

4,622 (69.23)

116,572 (68.34)

 

—

—

 

≥11

1,226 (18.36)

35,747 (20.96)

 

—

—

 

PSA (ng/mL)

  

<0.001

  

<0.001

<10

565 (8.46)

111,893 (65.60)

 

7 (6.42)

769 (62.72)

 

10–20

549 (8.22)

21,850 (12.81)

 

7 (6.42)

182 (14.85)

 

>20

4,851 (72.66)

12,615 (7.40)

 

84 (77.06)

131 (10.69)

 

Unknow

711 (10.65)

24,221 (14.20)

 

11 (10.09)

144 (11.75)

 

Gleason’s Score

  

<0.001

  

<0.001

≤6

5,042 (75.52)

164,624 (96.51)

 

4 (3.67)

444 (36.22)

 

7

4 (0.06)

1,164 (0.68)

 

7 (6.42)

460 (37.52)

 

≥8

8 (0.12)

198 (0.12)

 

52 (47.71)

240 (19.58)

 

Unknown

1622 (24.30)

4597 (2.69)

 

46 (42.20)

82 (6.69)

 

Gradec

  

<0.001

   

G1

12 (0.18)

2,870 (1.68)

 

—

—

 

G2

212 (3.18)

68,361 (40.08)

 

—

—

 

G3

4,834 (72.41)

91,848 (53.84)

 

—

—

 

G4

67 (1.00)

298 (0.17)

 

—

—

 

Unknown

1,551 (23.23)

7,202 (4.22)

 

—

—

 

Stage

  

<0.001

—

—

 

I

0

157 (0.09)

 

—

—

 

II

0

140,042 (82.10)

 

—

—

 

III

0

13,908 (8.15)

 

—

—

 

IV

6,676 (100)

5,505 (3.23)

 

—

—

 

Unknown

0

10,967 (6.43)

 

—

—

 

T stage

  

<0.001

  

<0.001

T1

1,792 (26.84)

68,109 (39.93)

 

24 (22.02)

487 (37.28)

 

T2

1,993 (29.85)

78,254 (45.88)

 

29 (26.61)

531 (43.31)

 

T3

669 (10.02)

17,131 (10.04)

 

13 (11.93)

140 (11.42)

 

T4

784 (11.74)

876 (0.51)

 

7 (6.42)

9 (0.73)

 

Unknown

1,438 (21.54)

6,209 (3.64)

 

36 (33.03)

89 (7.26)

 

N stage

  

<0.001

  

<0.001

N0

3,725 (55.80)

157,451 (92.30)

 

56 (51.38)

1,078 (87.93)

 

N1

1,557 (23.32)

3,162 (1.85)

 

19 (17.43)

25 (2.04)

 

N2

1,394 (20.88)

9,966 (5.84)

 

34 (31.19)

123 (10.03)

 

Surgery

  

<0.001

  

<0.001

Yes

764 (11.44)

71,210 (41.75)

 

11 (10.09)

458 (37.36)

 

Not-Recommended

5,693 (85.28)

88,224 (51.72)

 

—

—

 

No

219 (3.28)

11,145 (6.53)

 

98 (89.91)

768 (62.64)

 

Radiation

  

<0.001

  

0.001

Yes

1,663 (24.91)

54,871 (32.17)

 

19 (17.43)

407 (33.2)

 

No

5,013 (75.09)

115,708 (67.83)

 

90 (82.57)

819 (66.80)

 
  1. aDivorced includes separated; Single includes unmarried and widowed.
  2. bComposite socioeconomic status.
  3. cG1: well differentiated; G2: moderately differentiated; G3: poorly differentiated; G4: undifferentiated; NOS: not otherwise specified; SEER: Surveillance, Epidemiology, and End Results.
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