Table 2 Forced peak inspiratory flow rates against different simulated internal resistances of dry powder inhalers.

From: Inappropriate Peak Inspiratory Flow Rate with Dry Powder Inhaler in Chronic Obstructive Pulmonary Disease

Variable

Internal resistance

Med-high

Medium

Med-low

Low

Age, years

<65

68 (36–85)

75.5 (44–95)

84 (47–103)

103.5 (62–128)

65–70

63.5 (21–95)

72 (25–103)

80 (26–113)

100 (34–150)

70–75

64.5 (40–98)

74.5 (46–90)

86 (53–116)

103.5 (66–128)

75–80

57 (28–85)

70 (38–86)

75 (46–98)

93 (58–135)

≥80

58 (28–82)

65.5 (35–83)

76.5 (38–95)

91.5 (43–115)

p value

0.126

0.204

0.188

0.124

Body mass index, kg/m2

<18.5

70.5 (52–79)

76 (56–80)

86 (69–95)

104 (78–112)

18.5–24

59 (21–88)

66.5 (25–90)

75 (26–101)

95 (34–150)

24–27

66 (28–95)

72 (35–103)

82.5 (38–113)

102 (43–140)

≥27

62 (34–98)

74 (42–95)

86 (51–116)

103 (61–122)

p Value

0.283

0.068

0.036

0.300

Sex

Man

63 (21–98)

71 (25–103)

81 (26–116)

98 (34–150)

Woman

56 (28–74)

60 (40–75)

73 (46–88)

89 (64–110)

p Value

0.171

0.04

0.077

0.182

mMRC

Grade 0

46 (28–62)

51.5 (40–76)

57.5 (46–91)

70 (64–113)

Grade 1

64 (28–98)

72 (38–103)

84 (40–116)

97 (52–140)

Grade 2

60.5 (21–95)

70 (25–95)

78 (26–110)

97 (34–135)

Grade 3

63 (34–88)

70.5 (38–90)

82 (46–103)

102.5 (58–150)

p Value

0.138

0.140

0.157

0.275

COPD GOLD stage

GOLD 1

62.5 (28–98)

71.5 (38–90)

82.5 (40–116)

96.5 (52–135)

GOLD 2

61.5 (21–95)

70 (25–103)

78 (26–113)

97 (34–140)

GOLD 3

62.5 (34–85)

67.5 (38–86)

79.5 (46–103)

101 (58–122)

GOLD 4

70 (68–88)

86 (74–90)

98 (86–101)

122 (103–150)

p Value

0.348

0.184

0.378

0.083

COPD GOLD group

Group A

62.5 (28–98)

72 (40–90)

85 (46–116)

97 (64–135)

Group B

61.5 (21–95)

70 (25–103)

78 (26–113)

97 (34–140)

Group C

60 (34–84)

65 (38–86)

70 (46–102)

91 (58–122)

Group D

63.5 (40–88)

71 (44–90)

82 (61–103)

103 (68–150)

p Value

0.758

0.736

0.638

0.400

  1. Data presented as median (range).
  2. GOLD: Global Initiative for Chronic Obstructive; mMRC, modified medical research council.