Table 1 Baseline characteristic according to Dtotal status at diagnosis.

From: Impact of season on the association between vitamin D levels at diagnosis and one-year remission in early Rheumatoid Arthritis

 

Low Dtotal (<50 nmol/L) N = 67 (42%)

Normal Dtotal (≥50 nmol/L) N = 91 (58%)

Group comparison (p-value)

Total N = 158

Age at inclusion, Years

Median 52

IQR 44–63

Median 53

IQR 41–63

0.83

Median 53

IQR 43–63

Female sex

N = 42 (63%)

N = 62 (68%)

0.48

N = 104 (66%)

Symptom duration prior to diagnosis, months

Median 3.3

IQR 2.4–4.8

Median 3.2

IQR 2.5–4.4

0.81

Median 3.2

IQR 2.5–4.6

Ciclosporin (yes)

N = 36 (54%)

N = 42 (46%)

0.35

N = 78 (49%)

ACPA-status positive

N = 39 (58%)

N = 53 (58%)

0.99

N = 92 (58%)

IgM-RF-status positive

N = 39 (58%)

N = 63 (69%)

0.15

N = 102 (65%)

NTJ (0 to 28)

Median 10

IQR 6–16

Median 10

IQR 5–15

0.25

Median 10

IQR 5–15

NSJ (0 to 28)

Median 9

IQR 5–12

Median 8

IQR 5–12

0.67

Median 8

IQR 5–12

VASpatient-global (0 to 100 mm)

Median 50

IQR 26–72

Median 50

IQR 29–72

0.61

Median 50

IQR 29–72

VASpatient-pain (0 to 100 mm)

Median 48

IQR 27–72

Median 46

IQR 29–72

0.96

Median 48

IQR 29–70

VASdoctor-global(0 to 100 mm)

Median 58

IQR 42–70

Median 55

IQR 36–68

0.41

Median 58

IQR 38–68

ESR, mm/hour

Median 32

IQR 9–48

Median 23

IQR 11–47

0.65

Median 28

IQR 10–47

CRP, nmol/L

Median 24

IQR 9–51

Median 17.3

IQR 9–39

0.19

Median 20.2

IQR 9–43

DAS28-CRP (0 to 9)

Median 5.3

IQR 5.6–6.1

Median 5.2

IQR 4.4–5.9

0.32

Median 5.3

IQR 4.5–5.9

HAQ (0 to 3)

Median 1

IQR 0.5–1.5

Median 0.9

IQR 0.4–1.5

0.88

Median 0.7

IQR 0.4–1.5

Creatinine µmol/L

Median 75

IQR 67–82

Median 77

IQR 68–83

0.53

Median 76

IQR 67–82

BMI ≥ 30 (kg/m2)

N = 20 (30%)

N = 12 (13%)

0.01

N = 32 (20%)

Weight, kg

Median 79

IQR 64–92

Median 73

IQR 64–82

0.03

Median 76

IQR 64–85

Height, cm

Median 170

IQR 166–175

Median 170

IQR 164–175

0.76

Median 170

IQR 165–175

1,25(OH)2D, pmol/L

Median 82

IQR 65–99

Median 110

IQR 80–139

<0.001

Median 95.5

IQR 70–119

Season of diagnosis (Winter)

N = 44 (66%)

N = 37 (41%)

0.002

N = 81 (51%)

  1. Abbreviations: Dtotal: The sum of 25OHD2 and 25OHD3. ACPA: Anti Citrullinated Protein Antibodies, IgM-RF: Immunoglobulin M Rheumafactor, NTJ: Number of Tender Joints, NSJ: Number of Swollen Joints, VAS: Visual Analogue Score, ESR: Erythrocyte Sedimentation rate, CRP: C-reactive protein, DAS28-CRP Disease Activity Score, based on 28 joint count and CRP. HAQ: Health Assessment Questionnaire, BMI: Body Mass Index. Data as observed. Significant results in bold.
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