Figure 3
Multi-Unit Activity (MUA) Data. (A) MUA activity (fractional changes of number of spikes/100 ms) along depth of the microelectrode and time (stimulation periods) for 2s-stimulation in 100% oxygen. Cortical regions are at the depth of channels 3–8 (biggest responses in MUA). (B) Time-series of mean total responses of MUA (fractional changes in spikes/100 ms) ±SEM. (i) 2s-stimulation in 100% oxygen: WT-MUA 547.52 ± 98.7 spikes/100 ms, J20-MUA 2260.78 ± 710.8 spikes/100 ms. (ii) 2s-stimulation in 21% oxygen: WT-MUA 676.1 ± 143.35 spikes/100 ms, J20-MUA 2318.16 ± 932.9 spikes/100 ms. (iii) 16s-stimulation in 100% oxygen: WT-MUA 4722.73 ± 914.8 spikes/100 ms, J20-MUA 14,158.4 ± 4753.2 spikes/100 ms. (iv) 16s-stimulation in 21% oxygen: WT-MUA 3974.8 ± 796.8 spikes/100 ms, J20-MUA 13,592.8 ± 5184.6 spikes/100 ms. WT n = 6, J20-hAPP n = 5.
