Figure 1
From: miR-744-5p contributes to ocular inflammation in patients with primary Sjogrens Syndrome
Altered expression of microRNA-744-5p (miR-744-5p) and its target gene Pellino3 in conjunctival epithelial cells from patients with primary Sjogrens Syndrome (pSS) as compared with normal controls. (A) Microarray analysis of miRNA expression in primary conjunctival epithelial cells from patients with pSS and healthy controls. (A) Heatmap displaying relative expression of miRs in pSS patients compared to healthy controls (n = 5). (B) Independent verification in conjunctival epithelial cells of hsa-miR-744-5p expression in 19 pSS patients and 11 healthy controls (CTL) by quantitative real-time polymerase chain reaction (qPCR) analysis, **P ≤ 0.01. (C) Conjunctival epithelial cell expression of Pellino3 in 19 pSS patients and 11 healthy controls, as determined by qPCR analysis. Each data point represents a single subject; horizontal lines show the mean, *P ≤ 0.02 ***P ≤ 0.001.
