Table 2 PARP1 genotypes and disease-free survival.
Variables | Patients (%) | 5 y DFS(%) | Crude | Adjusted | ||
|---|---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |||
Rs1136410 | ||||||
TT | 94(34.6) | 69.4 | 1(Ref) | 1(Ref) | ||
TC | 134(49.3) | 73.3 | 0.791(0.463–1.351) | 0.391 | 0.891 (0.516–1.537) | 0.678 |
CC | 44(16.1) | 74.2 | 0.895(0.440–1.819) | 0.759 | 0.877(0.428–1.796) | 0.719 |
rs11801168 | ||||||
TT | 7(2.6) | 64.3 | 1(Ref) | 1(Ref) | ||
TC | 68(25.0) | 76.7 | 0.885(0.202–3.881) | 0.872 | 1.070(0.240–4.772) | 0.929 |
CC | 197(72.4) | 71.4 | 0.996(0.241–4.109) | 0.995 | 1.255(0.296–5.322) | 0.758 |
rs12568297 | ||||||
GG | 226(83.1) | 72.4 | 1(Ref) | 1(Ref) | ||
GC | 41(15.1) | 75.1 | 1.085(0.552–2.133) | 0.814 | 1.020(0.513–2.027) | 0.956 |
CC | 5(1.8) | 53.3 | 1.511(0.366–6.229) | 0.568 | 1.531(0.351–6.680) | 0.571 |
Rs6664761 | ||||||
TT | 33(12.1) | 68.3 | 1(Ref) | 1(Ref) | ||
TC | 119(43.8) | 74.6 | 0.537(0.261–1.102) | 0.090 | 0.564(0.272–1.171) | 0.124 |
CC | 120(44.1) | 70.5 | 0.712(0.358–1.417) | 0.333 | 0.755(0.376–1.516) | 0.429 |
Rs7531668 | ||||||
TT | 163(59.9) | 69.2 | 1(Ref) | 1(Ref) | ||
TA | 78(28.7) | 79.3 | 0.594(0.319–1.108) | 0.102 | 0.526(0.280–0.990) | 0.046 |
AA | 31(11.4) | 69.6 | 1.335(0.669–2.662) | 0.412 | 1.190(0.588–2.406) | 0.629 |
