Table 3 PARP1 genotypes and overall survival.
Variables | 5 y OS(%) | Crude | Adjusted | ||
|---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | ||
rs1136410 | |||||
TT | 87.3 | 1(Ref) | 1(Ref) | ||
TC | 90.5 | 0.578(0.239–1.395) | 0.222 | 0.818(0.334–2.008) | 0.662 |
CC | 77.1 | 1.382(0.555–3.439) | 0.487 | 1.572(0.607–4.073) | 0.352 |
rs11801168 | |||||
TT | 85.7 | 1(Ref) | 1(Ref) | ||
TC | 91.5 | 0.344(0.066–1.788) | 0.204 | 0.663 (0.123–3.570) | 0.632 |
CC | 85.3 | 0.486(0.113–2.090) | 0.332 | 0.990(0.214–4.577) | 0.990 |
Rs12568297 | |||||
GG | 85.5 | 1(Ref) | 1(Ref) | ||
GC | 95.0 | 0.470(0.111–1.989) | 0.305 | 0.451(0.105–1.942) | 0.285 |
CC | 80.0 | 2.823(0.658–12.110) | 0.162 | 1.678(0.343–8.214) | 0.523 |
Rs6664761 | |||||
TT | 85.2 | 1(Ref) | 1(Ref) | ||
TC | 90.4 | 0.772(0.205–2.915) | 0.703 | 1.079(0.279–4.178) | 0.912 |
CC | 84.4 | 1.522(0.446–5.196) | 0.503 | 1.974(0.563–6.919) | 0.288 |
Rs7531668 | |||||
TT | 84.3 | 1(Ref) | 1(Ref) | ||
TA | 91.4 | 0.486 (0.183–1.289) | 0.147 | 0.483(0.180–1.292) | 0.147 |
AA | 90.4 | 0.499(0.117–2.130) | 0.348 | 0.376(0.087–1.628) | 0.191 |
