Table 1 Correlation of Ki-67 and tumoral grade in breast cancer patients among IHC-based subtypes.

From: Effect of Ki-67 Expression Levels and Histological Grade on Breast Cancer Early Relapse in Patients with Different Immunohistochemical-based Subtypes

 

Ki-67 (continuous)

Ki-67 (categorical)*

Median (IQR)

P

Low

High

P

All patients

 

< 0.001

  

< 0.001

    Grade 1, 2

0.1 (0.05–0.2)

 

966

743

 

    Grade 3

0.3 (0.15–0.5)

 

204

660

 

Luminal-like

 

< 0.001

  

< 0.001

    Grade 1, 2

0.1 (0.05–0.2)

 

803

430

 

    Grade 3

0.2 (0.1–0.4)

 

115

246

 

HER2-positive

 

< 0.001

  

< 0.001

    Grade 1, 2

0.2 (0.1–0.3)

 

130

256

 

    Grade 3

0.3 (0.15–0.4)

 

55

252

 

TNBC

 

< 0.001

  

< 0.001

    Grade 1, 2

0.2 (0.1–0.45)

 

33

57

 

    Grade 3

0.4 (0.2–0.65)

 

34

162

 
  1. Abbreviations: IHC-based, immunohistochemical-based; HER2, human epidermal growth factor receptor 2; TNBC, triple-negative breast cancer; IQR, interquartile rage.
  2. * Ki-67 median = 15%, Ki-67 Low <15%, Ki-67 High ≥ 15%.
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