Figure 4
Multicontrast MRN in STZ-diabetic mice at ultra high field strength. (a–f) Illustration and corresponding quantitative findings of the six MR contrasts ‘T2wnorm‘ at proximal (i.e. pelvic level) and distal (i.e. thigh level) positions, ‘T2-time’, ‘proton density (PD)’, ‘fractional anisotropy (FA)’ and ‘apparent diffusion coefficient (ADC)’. Each pair of images shows a representative image example of the control (Ctrl) and STZ group, respectively. A comparison of the respective quantitative group data is provided underneath, given as group mean ± s.d. N = 20 vs. 26 nerves. *p < 0.05, ****p < 0.0001, n.s. = nonsignificant, unpaired two-sided t-test. White arrows indicating sciatic nerves.
