Table 1 Demographics of sample.

From: Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: A 7 T imaging study

N = 53

Mean (sd) n (%)

Range

Demographics

Age (in years)

45.05 (18.2)

21–73

Female (%)

31 (57.4)

 

Educationa

5.51 (1.6)

2–8

Neuropsychological assessment

HDRS-score

1.16 (1.8)

0–8

MMSE-score

29.38 (0.7)

27–30

WLT learning (number of words)

52.09 (8.3)

32–71

WLT delayed recall (number of words)

11.05 (2.8)

1–15

SWCT interference score

35.96 (15.6)

−2.3–69.8

LDST (number correct)

57.12 (10.6)

37–87

CST mental flexibility score

7.31 (4.7)

−2.1–19.8

Verbal Fluency animals (number words)

26.57 (6.2)

11–38

Verbal Fluency professions (number words)

18.41 (4.8)

11–32

Verbal Fluency M (number words)

17.20 (5.6)

7–31

LDI-score

0.16 (0.18)

−0.15–0.47

CRS

0.58 (0.25)

−0.02–0.90

Subfield volumeb

Left CA1

30.63 (3.2)

22.2–38.1

Right CA1

31.19 (3.3)

24.1–38.9

Left CA3

9.69 (1.1)

7.3–12.1

Right CA3

10.48 (1.2)

7.7–12.8

Left DG

13.88 (1.3)

11.2–16.2

Right DG

14.29 (1.4)

10.4–16.8

Subfield activationc

Left CA1

3.09 (21.5)

−38.6–117.0

Right CA1

1.98 (17.1)

−52.7–47.1

Left CA3

−0.81 (29.1)

−92.1–65.1

Right CA3

2.31 (27.1)

−48.2–79.7

Left DG

8.11 (47.4)

−91.2–275.6

Right DG

5.51 (34.3)

−57.8–149.5

  1. Note: HDRS: Hamilton Depression Rating Scale; MMSE: Mini Mental State Examination; WLT: Word learning test; SWCT: Stroop word colour test; LDST: Letter digit substitution test; CST: Concept shifting test; LDI: Lure Discrimination Index; CRS: Corrected Recognition Score. MMSE, WLT, Stroop, LDST, CST, and Verbal Fluency are corrected for age, sex, and education, CA: Cornu Ammonis, DG: dentate gyrus.
  2. ªA standardized 8-point scale (CBS, 2011) was used to indicate educational level (range 1 = primary school to 8 = university).
  3. bSubfield volume is expressed as raw volume in mm3 divided by intracranial volume in mm3 and multiplied by 1000 (arbitrary unit).
  4. cActivation contrast is successful vs. unsuccessful pattern separation.