Figure 6
From: Cell-specific metabolomic responses to injury: novel insights into blood-brain barrier modulation
AC have a greater adaptive capacity to face environmental stress. Modulation of cellular ATP concentrations under different conditions. Abundance of ATP cycle-related metabolites, ADP (b) and AMP (c) under different conditions. d,e Amount of creatine (d) and phosphocreatine (e) under different conditions. AC and EC were exposed to normoxia (NX), hypoxia (HX) and near anoxia (AX) with or without glucose (±Glc) for 24 h. Data compared to baseline conditions (NX + Glc) in each cell type. The ATP data presented as mean ± SD of n = 3 (in EC) and n = 7 (in AC) independent experiments, and the LC-MS data showed as mean ± SD of n = 4 biological replicates. *P < 0.05, **P < 0.01, ***P < 0.001; 1-way ANOVA.
