Table 3 Comparison of cost-per-positive (£) by sample type for 16S rRNA PCR positive results at a London NHS laboratory network, April 2015 and April 2019.

From: Clinical utility and cost-effectiveness of bacterial 16S rRNA and targeted PCR based diagnostic testing in a UK microbiology laboratory network

Samples referred

Number sent

Cost(£)/positive 16S rRNA

Cost(£)/positive 16S rRNA and negative culture

Pus

84

149.17

227.68

CSF

149

959.19

1278.92

Tissue/Biopsy

131

481.89

674.65

Joint Fluid

157

621.96

898.39

Pleural Fluid

45

463.50

463.50

Bronchial Alveolar Lavage

9

154.50

154.50

Other

32

274.67

549.33

All samples

607

400.78

568.37