Table 2 Effect of treatment with mesenchymal stem cells (MSC) or MSC associated with FSH on the number of matured COC, cleaved embryos and day-7 blastocysts in Gir (Bos indicus) cows that previously underwent multiple OPU sessions and had a history of low embryo production.

From: Intraovarian injection of mesenchymal stem cells improves oocyte yield and in vitro embryo production in a bovine model of fertility loss

Endpoint

Group

OPU session

1

2

3

COC matured

 

Control

2.5 ± 1.1

2.0 ± 0.6

2.4 ± 1.3

 

MSC

3.1 ± 0.6

3.3 ± 1.4

4.7 ± 2.6

 

MSC + FSH

3.5 ± 0.8

4.5 ± 1.4

3.5 ± 1.0

Cleaved

 

Control

2.3 ± 1.1

1.6 ± 0.5

2.2 ± 1.1

 

MSC

2.3 ± 0.5

2.3 ± 0.9

4.0 ± 1.6

 

MSC + FSH

2.5 ± 0.5

3.5 ± 1.3

3.0 ± 0.7

Blastocysts

 

Control

0.2 ± 0.2

0.4 ± 0.4

0.2 ± 0.2

 

MSC

0.3 ± 0.3

0.0 ± 0.0

0.2 ± 0.2

 

MSC + FSH

0.3 ± 0.2

0.2 ± 0.2

0.0 ± 0.0