Table 3 Two-component analysis of integral calcium release fluxes. Amplitudes and fractions are given as mean ± s.e.m. obtained from 15 CTR and 17 IMY traces. Amplitude – amplitudes of the best fit curves to CRF records. Student’s t-test p-values for equal means between the CTR and IMY groups were P = 0.01 for the early components, and P = 2.2E-5 for the late components. Fraction – the amplitude of one component of release flux divided by the sum of amplitudes of early and late components; calculated for each best fit curve. Student’s t-test p-values for equal means between the CTR and IMY groups were P = 2.7E-5 for the both, early and late components. Lat – latencies of the best fit the early and late components estimated for all 32 (CTR plus IMY) curves collectively, given as mean ± standard error of the fit.TTP and FDHM were determined from the simulated curves of the early and late components visualized in Fig. 4 (bottom).The same experimental data set as in Table 2.

From: Structural variability of dyads relates to calcium release in rat ventricular myocytes