Table 1 Patient characteristics and baseline data at the time of enrollment in Phase 1 clinic.

From: First-In-Human Phase 1 Clinical Trials – A Single-Center Experience In The Era Of Modern Oncotherapeutics

Variable

N (%)(range)

Median Age

54.4

Caucasian

129 (80%)

African Americans

32 (20%)

Male

76 (47%)

ECOG 0

59 (38%)

Immunotherapy (IOT)

40 (25%)

Targeted treatments (TT)

122 (75%)

Base line Albumin

4 (2.8–4.8)

Base line LDH

190.5 (109.0–895.0)

Prior Rx ≤ 2

72 (44%)

Prior Rx 3–4

52 (32%)

Prior Rx ≥ 5

38 (24%)

Prior Radiation

72 (45%)

Hematological malignancies

55 (34%)

Non-Hematological Malignancies

107 (66%)

  1. N = 162