Figure 1 | Scientific Reports

Figure 1

From: Autologous fecal transplantation from a lean state potentiates caloric restriction effects on body weight and adiposity in obese mice

Figure 1

Schematic design of the experiment and effects of fecal microbiota transplantation (FMT) on body weight gain, feed efficiency and adiposity. (A) Schematic design of the experiment. (B) Body weight gain of mice fed with a control or HFD and submitted to CR with and without FMT. (C) Metabolic efficiency ratio representing the body weight gain relative to energy intake among the groups. (D) Effects of CR and FMT on subcutaneous, mesenteric, retroperitoneal, epididymal and total visceral fat weights in control and HFD-induced obese mice. (E) Representative H&E staining of mesenteric and retroperitoneal fat depots. Scale bar, 10 µm. (F-I) Quantification of number and size of adipocytes per area (627.42 × 468.29 µm). (J) Effects of CR and FMT on mesenteric GLUT4 mRNA levels. Data are expressed as mean ± SEM of at least 8 animals per group. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs Control; #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001 vs HFD, ap < 0.05 vs CR, $p < 0.05, $$p < 0.01 vs FT-H.

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