Table 3 Correlation of serum levels of the 11 arachidonic acid metabolites with that of the inflammatory biomarkers in 75 patients with stable coronary artery disease.

From: Association of Arachidonic Acid-derived Lipid Mediators with Subsequent Onset of Acute Myocardial Infarction in Patients with Coronary Artery Disease

 

hs-CRP

Adiponectin

LppPLA2

IL6

TNF-α

MMP-9

NT-pro-BNP

8-HETE

r

−0.042

−0.010

0.186

0.010

0.294

0.105

0.438

P value

0.737

0.936

0.128

0.934

<0.05

0.395

<0.001

9-HETE

r

−0.028

−0.011

0.203

0.005

0.316

0.104

0.425

P value

0.819

0.931

0.098

0.970

<0.01

0.397

<0.001

11-HETE

r

0.063

−0.016

0.196

0.120

0.271

0.108

0.233

P value

0.608

0.898

0.110

0.331

<0.05

0.382

0.048

12-HETE

r

−0.043

−0.011

0.192

0.001

0.292

0.102

0.437

P value

0.729

0.931

0.120

0.991

<0.05

0.412

<0.001

15-HETE

r

−0.037

−0.013

0.187

0.007

0.293

0.106

0.437

P value

0.762

0.919

0.126

0.952

<0.05

0.391

<0.001

19-HETE

r

−0.008

−0.004

0.216

0.005

0.298

0.100

0.413

P value

0.949

0.973

0.077

0.970

<0.05

0.417

<0.001

20-HETE

r

−0.025

−0.010

0.204

0.018

0.302

0.104

0.433

P value

0.840

0.934

0.098

0.888

<0.05

0.401

<0.001

5,6-EET

r

−0.035

−0.012

0.176

0.003

0.302

0.090

0.427

P value

0.774

0.923

0.148

0.978

<0.05

0.463

<0.001

8,9-EET

r

−0.042

−0.014

0.190

−0.006

0.340

0.128

0.393

P value

0.732

0.909

0.117

0.963

<0.005

0.295

0.001

11,12-EET

r

0.053

−0.046

0.200

0.115

0.214

0.092

0.168

P value

0.667

0.708

0.100

0.346

0.077

0.450

0.157

14,15-EET

r

−0.019

−0.008

0.163

0.008

0.252

0.080

0.394

P value

0.874

0.951

0.180

0.945

<0.05

0.516

0.001

  1. Pearson’s correlation coefficient was used to evaluate the relation between the levels of arachidonic acid metabolites and biomarkers. hs-CRP, high-sensitivity C-reactive protein; IL 6, interleukin 6; Lp-PLA2, lipoprotein-associated phospholipase A2; MMP-9, matrix metalloproteinase-9; NT-pro BNP, N-terminal pro b-type natriuretic peptide; TNF-α, tumor necrosis factor-alpha.