Figure 3
From: Co-chaperones DNAJA1 and DNAJB6 are critical for regulation of polyglutamine aggregation
Filter trap assays shows that KO DNAJA1 and DNAJB6 alters polyQ74htt-GFP aggregation. (A) Representative image of the assay. (B) Data analysis of 5 filter trap assays, the value of the intensity band of each assay is divided by the parental band, in order to obtain the fold change of aggregates of the specific knock out cell lines. Membranes were analysed by probing with anti-GFP antibody. *p < 0.05, ***p < 0.001, analysed by one-way ANOVA. (n = 5).
