Figure 5
Cyclin D2−/− mice are able to learn a visual discrimination task. (A) The touchscreen chamber for the visual discrimination task was set up to contain two lit boxes which were separated by two unlit boxes. (B) Graphical outline of the experimental paradigm for the visual discrimination task. (C) No genotype difference was seen in the number of sessions required to reach criterion of 80% selection for two consecutive days, indicating normal acquisition of the task. (D) Days to criterion, representing the proportion of individual subjects that completed acquisition at each training day (survival curve). Cyclin D2−/− mice were able to acquire the visual discrimination task equally well as WT mice. (E) Memory was tested at 1, 2, 4, and 8 weeks after the completion of acquisition. There were no genotype differences at any time point.
