Table 2 Comparison of incidence rates and hazard ratios for overall and specific cancers between control and glaucoma groups.
From: Risk of cancer in patients with glaucoma: A nationwide population-based cohort study
Control (N = 107536) | Glaucoma (N = 107536) | Hazard ratio (95% confidence interval) | |||||
|---|---|---|---|---|---|---|---|
N. of events | Incidence rate (per 1000) | N. of events | Incidence rate (per 1000) | Model 1 | Model 2 | Model 3 | |
Overall cancer | 5802 | 11.617 | 6086 | 12.227 | 1.053 (1.015, 1.091)* | 1.051 (1.014, 1.09)* | 1.049 (1.012, 1.088)* |
Oral | 89 | 0.174 | 106 | 0.207 | 1.192 (0.899, 1.58) | 1.191 (0.898, 1.578) | 1.217 (0.917, 1.616) |
Esophagus | 103 | 0.201 | 81 | 0.158 | 0.787 (0.588, 1.053) | 0.784 (0.586, 1.049) | 0.805 (0.6, 1.079) |
Laryngeal | 48 | 0.094 | 53 | 0.104 | 1.105 (0.748, 1.634) | 1.102 (0.746, 1.629) | 1.147 (0.773, 1.7) |
Thyroid | 456 | 0.892 | 447 | 0.876 | 0.981 (0.861, 1.118) | 0.982 (0.862, 1.118) | 0.997 (0.874, 1.137) |
Stomach | 1015 | 1.990 | 954 | 1.872 | 0.941 (0.861, 1.028) | 0.938 (0.859, 1.025) | 0.935 (0.856, 1.022) |
Colorectal | 1162 | 2.279 | 1227 | 2.410 | 1.058 (0.976, 1.146) | 1.056 (0.974, 1.144) | 1.04 (0.959, 1.127) |
Liver | 679 | 1.327 | 707 | 1.383 | 1.043 (0.938, 1.158) | 1.04 (0.936, 1.156) | 1.016 (0.914, 1.13) |
Pancreatic | 505 | 0.986 | 545 | 1.066 | 1.081 (0.958, 1.22) | 1.078 (0.955, 1.217) | 1.055 (0.934, 1.191) |
Biliary | 300 | 0.586 | 285 | 0.557 | 0.951 (0.809, 1.118) | 0.947 (0.806, 1.114) | 0.935 (0.795, 1.101) |
Lung | 982 | 1.921 | 1007 | 1.972 | 1.027 (0.94, 1.121) | 1.023 (0.937, 1.117) | 1.059 (0.97, 1.157) |
Renal | 139 | 0.271 | 178 | 0.348 | 1.282 (1.027, 1.601) | 1.281 (1.026, 1.599) | 1.239 (0.991, 1.549) |
Bladder | 233 | 0.455 | 234 | 0.457 | 1.005 (0.839, 1.205) | 1 (0.834, 1.199) | 0.998 (0.831, 1.198) |
Cancer of central nervous system | 102 | 0.199 | 108 | 0.211 | 1.06 (0.809, 1.39) | 1.059 (0.808, 1.388) | 1.074 (0.818, 1.409) |
Leukemia | 98 | 0.191 | 102 | 0.199 | 1.042 (0.79, 1.375) | 1.04 (0.788, 1.373) | 1.03 (0.779, 1.361) |
Lymphoma | 126 | 0.246 | 146 | 0.285 | 1.16 (0.914, 1.472) | 1.158 (0.912, 1.469) | 1.19 (0.937, 1.513) |
Multiple myeloma | 57 | 0.111 | 60 | 0.117 | 1.054 (0.733, 1.514) | 1.051 (0.731, 1.51) | 1.033 (0.718, 1.488) |
Skin | 18 | 0.035 | 36 | 0.070 | 2.003 (1.138, 3.527)* | 2 (1.136, 3.521)* | 1.944 (1.102, 3.43)* |
Prostate | 625 | 2.427 | 732 | 2.849 | 1.174 (1.055, 1.307)* | 1.17 (1.052, 1.302)* | 1.168 (1.049, 1.3)* |
Testicular | 12 | 0.046 | 15 | 0.058 | 1.252 (0.586, 2.676) | 1.25 (0.585, 2.67) | 1.289 (0.6, 2.768) |
Breast | 278 | 1.099 | 324 | 1.284 | 1.167 (0.995, 1.37) | 1.169 (0.996, 1.372) | 1.168 (0.994, 1.372) |
Uterine cervical | 82 | 0.324 | 67 | 0.265 | 0.818 (0.592, 1.13) | 0.818 (0.592, 1.129) | 0.814 (0.588, 1.126) |
Uterine corpus | 53 | 0.209 | 56 | 0.221 | 1.058 (0.726, 1.54) | 1.058 (0.727, 1.54) | 1.051 (0.72, 1.535) |
Ovarian | 111 | 0.438 | 93 | 0.367 | 0.839 (0.637, 1.105) | 0.839 (0.637, 1.105) | 0.845 (0.64, 1.115) |
