Table 3 Comparison of incidence rates and hazard ratios for overall and specific cancers between control and glaucoma groups in men.
From: Risk of cancer in patients with glaucoma: A nationwide population-based cohort study
Control (N = 54621) | Glaucoma (N = 54621) | Hazard ratio (95% confidence interval) | |||||
|---|---|---|---|---|---|---|---|
N. of events | Incidence rate (per 1000) | N. of events | Incidence rate (per 1000) | Model 1 | Model 2 | Model 3 | |
Overall cancer | 3582 | 14.256 | 3713 | 14.832 | 1.041(0.994, 1.09) | 1.038 (0.992, 1.087) | 1.039 (0.992, 1.088) |
Oral | 54 | 0.209 | 79 | 0.305 | 1.465 (1.036, 2.07)* | 1.463 (1.035, 2.067)* | 1.491 (1.052, 2.114)* |
Esophagus | 96 | 0.371 | 76 | 0.294 | 0.792 (0.586, 1.071) | 0.789 (0.584, 1.066) | 0.811 (0.599, 1.098) |
Laryngeal | 44 | 0.170 | 50 | 0.193 | 1.138 (0.759, 1.706) | 1.135 (0.757, 1.701) | 1.178 (0.783, 1.773) |
Thyroid | 104 | 0.402 | 115 | 0.445 | 1.107 (0.849, 1.443) | 1.108 (0.85, 1.444) | 1.091 (0.835, 1.425) |
Stomach | 729 | 2.834 | 681 | 2.651 | 0.935(0.843, 1.038) | 0.933(0.84, 1.035) | 0.934(0.841, 1.038) |
Colorectal | 721 | 2.802 | 710 | 2.762 | 0.986(0.889, 1.093) | 0.983(0.886, 1.09) | 0.967(0.871, 1.073) |
Liver | 487 | 1.885 | 498 | 1.930 | 1.024(0.904, 1.16) | 1.022 (0.902, 1.158) | 0.993 (0.876, 1.126) |
Pancreatic | 300 | 1.160 | 316 | 1.223 | 1.055 (0.901, 1.235) | 1.051 (0.898, 1.231) | 1.026 (0.875, 1.203) |
Biliary | 180 | 0.695 | 144 | 0.557 | 0.801 (0.643, 0.997)* | 0.797 (0.64, 0.992)* | 0.796 (0.639, 0.993)* |
Lung | 746 | 2.890 | 713 | 2.765 | 0.957 (0.864, 1.06) | 0.952 (0.859, 1.055) | 0.995 (0.898, 1.104) |
Renal | 100 | 0.386 | 120 | 0.464 | 1.201 (0.921, 1.567) | 1.2 (0.921, 1.565) | 1.132 (0.866, 1.479) |
Bladder | 191 | 0.739 | 198 | 0.766 | 1.038 (0.851, 1.266) | 1.032 (0.846, 1.259) | 1.029 (0.842, 1.257) |
Cancer of central nervous system | 55 | 0.212 | 56 | 0.216 | 1.02 (0.703, 1.479) | 1.016 (0.701, 1.474) | 1.054 (0.725, 1.533) |
Leukemia | 55 | 0.212 | 61 | 0.236 | 1.111 (0.771, 1.599) | 1.108 (0.77, 1.595) | 1.095 (0.759, 1.58) |
Lymphoma | 87 | 0.336 | 85 | 0.329 | 0.978 (0.725, 1.318) | 0.975 (0.723, 1.314) | 1.013 (0.75, 1.369) |
Multiple myeloma | 30 | 0.116 | 37 | 0.143 | 1.235 (0.763, 1.999) | 1.229 (0.76, 1.99) | 1.189 (0.733, 1.93) |
Skin | 4 | 0.015 | 18 | 0.070 | 4.511 (1.527, 13.328)* | 4.5 (1.523, 13.296)* | 4.42 (1.493, 13.086)* |
Prostate | 625 | 2.427 | 732 | 2.849 | 1.174 (1.055, 1.307)* | 1.17 (1.052, 1.302)* | 1.168 (1.049, 1.3)* |
Testicular | 12 | 0.046 | 15 | 0.058 | 1.252 (0.586, 2.676) | 1.25 (0.585, 2.67) | 1.289 (0.6, 2.768) |
