Table 4 Comparison of incidence rates and hazard ratios for overall and specific cancers between control and glaucoma groups in women.
From: Risk of cancer in patients with glaucoma: A nationwide population-based cohort study
Control (N = 52915) | Glaucoma (N = 52915) | Hazard ratio (95% confidence interval) | |||||
|---|---|---|---|---|---|---|---|
N. of events | Incidence rate (per 1000) | N. of events | Incidence rate (per 1000) | Model 1 | Model 2 | Model 3 | |
Overall cancer | 2220 | 8.946 | 2373 | 9.591 | 1.072 (1.012, 1.136)* | 1.072 (1.011, 1.135)* | 1.07 (1.009, 1.134)* |
Oral | 35 | 0.138 | 27 | 0.107 | 0.772(0.467, 1.275) | 0.771(0.466, 1.273) | 0.791(0.478, 1.308) |
Esophagus | 7 | 0.028 | 5 | 0.020 | 0.715(0.227, 2.253) | 0.711(0.226, 2.241) | 0.702(0.222, 2.217) |
Laryngeal | 4 | 0.016 | 3 | 0.012 | 0.75 (0.168, 3.353) | 0.748 (0.167, 3.342) | 0.795 (0.177, 3.571) |
Thyroid | 352 | 1.395 | 332 | 1.317 | 0.944 (0.812, 1.096) | 0.944 (0.813, 1.097) | 0.969 (0.833, 1.127) |
Stomach | 286 | 1.131 | 273 | 1.080 | 0.955 (0.809, 1.127) | 0.953 (0.808, 1.125) | 0.94 (0.796, 1.111) |
Colorectal | 441 | 1.746 | 517 | 2.051 | 1.175 (1.034, 1.334)* | 1.174 (1.034, 1.333)* | 1.162 (1.023, 1.32)* |
Liver | 192 | 0.758 | 209 | 0.826 | 1.09 (0.896, 1.326) | 1.088 (0.894, 1.323) | 1.079 (0.886, 1.313) |
Pancreatic | 205 | 0.809 | 229 | 0.905 | 1.119 (0.926, 1.351) | 1.117 (0.925, 1.349) | 1.099 (0.909, 1.328) |
Biliary | 120 | 0.474 | 141 | 0.557 | 1.176 (0.922, 1.5) | 1.173 (0.92, 1.497) | 1.142 (0.894, 1.458) |
Lung | 236 | 0.932 | 294 | 1.163 | 1.248 (1.051, 1.481)* | 1.246 (1.05, 1.479)* | 1.264 (1.064, 1.501)* |
Renal | 39 | 0.154 | 58 | 0.229 | 1.489 (0.992, 2.235)* | 1.488 (0.992, 2.233)* | 1.519 (1.01, 2.283)* |
Bladder | 42 | 0.166 | 36 | 0.142 | 0.858 (0.55, 1.34) | 0.856 (0.548, 1.335) | 0.856 (0.548, 1.339) |
Cancer of central nervous system | 47 | 0.185 | 52 | 0.205 | 1.107 (0.746, 1.643) | 1.107 (0.746, 1.642) | 1.105 (0.743, 1.643) |
Leukemia | 43 | 0.170 | 41 | 0.162 | 0.954 (0.622, 1.464) | 0.953 (0.621, 1.462) | 0.952 (0.619, 1.463) |
Lymphoma | 39 | 0.154 | 61 | 0.241 | 1.566 (1.048, 2.341)* | 1.565 (1.047, 2.339)* | 1.582 (1.057, 2.368)* |
Multiple myeloma | 27 | 0.107 | 23 | 0.091 | 0.853 (0.489, 1.488) | 0.852 (0.489, 1.486) | 0.863 (0.494, 1.51) |
Skin | 14 | 0.055 | 18 | 0.071 | 1.287 (0.64, 2.588) | 1.285 (0.639, 2.583) | 1.231 (0.611, 2.483) |
Breast | 278 | 1.099 | 324 | 1.284 | 1.167 (0.995,1.37) | 1.169 (0.996,1.372) | 1.168 (0.994,1.372) |
Uterine cervical | 82 | 0.324 | 67 | 0.265 | 0.818 (0.592, 1.13) | 0.818 (0.592, 1.129) | 0.814 (0.588, 1.126) |
Uterine corpus | 53 | 0.209 | 56 | 0.221 | 1.058 (0.726, 1.54) | 1.058 (0.727, 1.54) | 1.051 (0.72, 1.535) |
Ovarian | 111 | 0.438 | 93 | 0.367 | 0.839 (0.637, 1.105) | 0.839 (0.637, 1.105) | 0.845 (0.64, 1.115) |
