Figure 5

Correlation matrices of lipid mediators and biomarkers of the SABA trial; positive correlations are blue, negative correlations are red. Only correlations with a Spearman’s of p < 0.05 are plotted. The thinner the dot, the smaller the p-value. LMs are ordered by key enzyme. Left: total SABA patient cohort (n = 28), middle: NEDA patients (n = 12), right: active EDA RR-MS patients, i.e. Non-responders (n = 16). Exact values of the correlations are given in the Supplementary Material. CEL: contrast enhancing lesion, M0-M8: treatment phase of the trial.