Table 2 Hardy-Weinberg Equilibrium (HWE) calculations of patient SERT genotypes.

Genotype		all patients (n = 616)					imatinib patients (n = 319)					dasatinib patients (n = 297)
Genotype		obs (n)	exp (n)	allele freq.	χ²	P value	obs (n)	exp (n)	allele freq.	χ²	P value	obs (n)	exp (n)	allele freq.	χ²	P value
5-HTTLPR (rs4795541)	L	194	198				99	103				95	95
	LS	311	302	L = 0.5674			164	156	L = 0.5674			147	146	L = 0.5673
	S	111	115	S = 0.4326	0.4972	0.780	56	60	S = 0.4326	0.7119	0.701	55	56	S = 0.4327	0.0199	0.990
rs25531	A	535	535				277	278				258	259
	AG	78	78	A = 0.9318			41	40	A = 0.9326			37	37	A = 0.9341
	G	3	3	G = 0.0682	0.0075	0.996	1	1	G = 0.0674	0.1600	0.923	2	1	G = 0.0659	0.0723	0.964
STin2 VNTR (rs57098334)	12/12	242	236				121	122				121	113
	12/10	262	272				145	142				117	130
	12/09	16	19				8	9				8	10
	10/10	86	79	12 = 0.6185			41	41	12 = 0.6191			45	38	12 = 0.6178
	10/09	6	11	10 = 0.3571			2	5	10 = 0.3589			4	6	10 = 0.3552
	09/09	4	<1	09 = 0.0244	39.8473	0.00001	2	<1	09 = 0.0219	24.1537	0.0002	2	<1	09 = 0.0269	19.0302	0.0019

P value is a measure of the deviation from HWE. Text in bold indicates significant P values. Serotonin-transporter-linked polymorphic region (5-HTTLPR). Intron 2, 17 bp variable number of tandem repeats (STin2 VNTR); 12, 10 and 9 tandem repeat alleles (12, 10 and 09 respectively). Allele frequency (allele freq.). Observed genotype (obs); expected genotype (exp); “long” allele (L); “short” allele (S). Text in bold indicates statistical significance (P < 0.05).

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