Figure 1 | Scientific Reports

Figure 1

From: Landscape of immune cell gene expression is unique in predominantly WHO grade 1 skull base meningiomas when compared to convexity

Figure 1

Gene co-expression network reveals immune function to correlate strongly with meningioma location. (A) Gene dendrogram illustrating modules. The grey denotes genes which are not implicated with any modules. Labels indicate cytokines which are positively correlated with the module meta-gene expression (Pearson correlation>0.6, p < 0.05). (B) Boxplot depicting the correlation between location and meta-gene expression level of the only significant module with DAVID annotations (Mann Whitney p = 0.005). As indicated in (C), this module maps to diverse immune processes, and is therefore labeled as “immune response (universal)”. C: Gene ontology terms ranked by Bonferroni p-value.

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