Table 1 Genes selected for the TET1 affected genes model and their fold change in TET1 knockout experiment.

From: Measuring Cancer Hallmark Mediation of the TET1 Glioma Survival Effect with Linked Neural-Network Based Mediation Experiments

HGNC

Fold

Concordance

Gene Description

RAI14

5.9

69.6

Retinoic acid induced 14

HGSNAT

5.5

64.1

Heparan-alpha-glucosaminide N-acetyltransferase

PLAG24A

5.5

60.4

Phospholipase A2 group IVA

PARD3B

5.5

71.4

Par-3 family cell polarity regulator beta

ALS2CR11

5.5

50.4

Amyotrophic lateral sclerosis 2 chromosome region candidate 11

DALRD3

−3.8

67.5

DALR anticodon binding domain containing 3

MUC2

−3.7

58.4

Mucin 2, oligomeric mucus/gel-forming

ERCC5

−3.6

73.6

ERCC excision repair 5, endonuclease

GUSBP1

−3.6

50.3

Glucuronidase, beta pseudogene 1

RALYL

−3.4

55.9

RALY RNA binding protein-like

SIX6

−3.5

57.3

SIX homeobox 6

  1. Fold gives the average fold change of these genes in a TET1 knockdown experiment.
  2. Concordance gives the concordance of a univariate Cox proportional hazards model built on each respective gene.