Table 1 Demographic and clinical characteristics of 40 eligible patients with mCRC and association of sHLA-G plasma expression with their clinicopathological parameters.
Characteristic | n | (%) | sHLA-G median (range, U/ml) | p* |
|---|---|---|---|---|
mCRC | 116.4 (12.8–1552.7) |  | ||
  Age, yrs |  | |||
    ≤61.6 | 20 | 117.9 (43.1–1552.7) | 0.8604 | |
    >61.6 | 20 | 116.4 (12.8–806.0) |  | |
  Gender |  | |||
    Woman | 25 | 62.5 | 121.4 (43.1–1552.7) | 0.1464 |
    Man | 15 | 37.5 | 91.5 (12.8–254.5) |  |
  Primary tumor site |  | |||
    Colon | 22 | 55.0 | 110.04 (12.8–199.7) | 0.5054a |
    Rectum | 18 | 45.0 | 123.6 (43.1–1552.7) |  |
    Left colon | 8 | 20.0 | 113.8 (12.8–199.7) | 0.8112 |
    Right colon | 14 | 35.0 | 94.2 (44.4–806.0) |  |
  Radical surgery |  | |||
    Yes | 26 | 65.0 | 125.8 (48.4–806.0) | 0.1605 |
    No | 14 | 35.0 | 89.3 (12.8–806.0) |  |
  Stage at diagnosis |  | |||
    I-II | 5 | 12.5 |  |  |
    III-IV | 35 | 87.5 |  |  |
  Adjuvant (radiotherapy or chemotherapy) |  | |||
    No | 26 | 65.0 | 102.0 (12.8–1552.7) | 0.6000 |
    Yes | 14 | 35.0 | 123.6 (61.8–366.5) |  |
  Number of metastatic sites |  | |||
    1 | 17 | 45.9 | 84.1 (43.1–711.4) | 0.0214 |
    >1 | 20 | 54.1 | 150.1 (12.8–1552.7) |  |
    2 | 12 | 32.4 |  |  |
    3 | 2 | 5.4 |  |  |
    4 | 5 | 13.5 |  |  |
    5 | 1 | 2.7 |  |  |
    >2 | 8 | 21.6 |  | 0.0486 |
