Table 3 Rs3737084, rs731821, and serum ferritin associations among 92 individuals with serum ferritin data.

From: Substantia nigra echogenicity is associated with serum ferritin, gender and iron-related genes in Parkinson’s disease

 

Gender (Male, %)

Age (years)

PD Duration (years)

H-Y

UPDRS-III

Ferritin (μg/L)

rs731821

Total (n = 184)

114 (62.0%)

63.7 ± 8.7

5.0 ± 3.8

2.3 ± 0.7

28.1 ± 12.6

186.9 ± 127.7

‘C’ (n = 138)

84 (60.9%)

63.9 ± 8.7

4.9 ± 4.0

2.3 ± 0.8

29.3 ± 13.2

191.8 ± 131.0

‘A’ (n = 46)

30 (65.2%)

63.2 ± 8.6

5.5 ± 3.3

2.2 ± 0.6

24.8 ± 10.0

172.4 ± 117.4

OR

0.83

0.99

1.12

0.92

0.96

1.00

95% CI

0.39–1.76

0.95–1.03

1.01–1.24

0.49–1.70

0.92–1.00

0.39–1.76

P

0.626

0.703

0.039

0.782

0.031

0.557

rs3737084

Total (n = 184)

114 (62.0%)

63.7 ± 8.7

5.0 ± 3.8

2.3 ± 0.7

28.1 ± 12.6

186.9 ± 127.7

‘C’ (n = 140)

82 (58.6%)

63.4 ± 8.5

5.0 ± 3.8

2.3 ± 0.7

28.2 ± 13.2

188.4 ± 130.9

‘G’ (n = 44)

32 (72.7%)

64.8 ± 9.1

5.2 ± 3.9

2.3 ± 0.7

28.0 ± 10.9

182.2 ± 118.5

OR

0.52

1.01

1.02

0.97

1.00

1.00

95% CI

0.24–1.14

0.97–1.06

0.92–1.13

0.52–1.82

0.96–1.04

1.00–1.00

P

0.102

0.527

0.734

0.931

0.991

0.557

  1. PD: Parkinson’s disease; H-Y: Hoehn and Yahr stage; UPDRS-III: Unified Parkinson Disease Rating Scale Part III, OR: odds ratio; PD: Parkinson’s disease; CI: confidential interval.
  2. P-values estimated from binary logistic regression models adjusted for age, gender, disease severity and disease duration.