Figure 2

Model dynamics of the untreated case. (a) Variables of the prostate gland compartment. (b) Variables of the lymphoid tissue compartment. The simulation time is 7 weeks (49 days). The variable dynamics are expressed in terms of fold-change with respect to their initial values. The experimental data (red dots) are compared to the simulated behaviors (solid lines). Within the tumor chart, the dark blue line represents the total tumor volume while the light blue line represents the predicted AIPC dynamics.