Table 2 Table of the model predicted best and worst treatment protocols.

From: A QSP model of prostate cancer immunotherapy to identify effective combination therapies

Number of combined treatments

Best combination

Worst combination

2

CX + ICB

V + AI

3

CX + V + ICB

V + AI + NK

4

V + AR + ICB + AM

V + AI + AR + AM

5

V + AR + NK + ICB + AM

CX + V + AI + AR + AM

6

CX + V + AR + NK + ICB + AM

CX + V + AI + AR + NK + AM

  1. The most and the least efficacious combination therapies sorted by the total number of treatments included in each therapy. Therapies are indicated by the following abbreviations: Androgen Deprivation (CX), Anti-IL-2 (AI), Anti-Treg (AR), Anti-MDSC (AM), Vaccine (V), infusion of NK cells (NK) and Immune-Checkpoint Blockade (ICB).
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