Table 1 Baseline demographic, clinical and biochemical characteristics of 22 patients with UC.

From: Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial

Characteristic

RIC

Sham

n = 11

n = 11

Age [years]

41 [36–64]

41 [24–50]

Sex [female]

2 [18%]

9 [82%]

Weight [kg]

78.2 [70.8–91.2]

70.0 [63.9–88.7]

BMI [kg/cm2]

25.4 [23.9–28.6]

26.3 [22.6–28.4]

Disease duration [years]

13.2 [8.3–14.9]

5.1 [2.2–12.3]

Smoking status

    Current

1 [9]

0[0]

   Former

7 [64]

7 [64]

   Never

3 [27]

4 [36]

Alcohol consumption

   ≥7/14 alcohol units per week

1 [9]

2 [18]

   <7/14 alcohol units per week

10 [91]

5 [45]

   No alcohol

0[0]

4 [36]

Disease extent at endoscopy

   Proctitis

4 [36]

6 [55]

   Left-sided UC

5 [45]

4 [36]

   Pancolitis

2 [18]

1 [9]

Montréal classification

   E1 - Ulcerative proctitis

3 [27]

4 [36]

    E2 - Left sided UC [distal UC]

7 [64]

6 [55]

    E3 - Extensive UC [pancolitis]

1 [9]

1 [9]

Medication

   No treatment

4 [36]

2 [18]

   Rectal 5-ASA

2 [18]

4 [36]

   Oral 5-ASA

6 [55]

8 [73]

    Immunosuppressants

1 [9]

1 [9]

   Anti-TNF

0

0

FC

1220 [523–1808]

1391 [879–4139]

P-CRP

1.95 [1.8–8.3]

1.9 [1.6–6.1]

Mayo Score

7 [6–8]

8 [7–9]

Endoscopic Mayo Score

2 [2–2.5]

2 [2–2.5]

Days of flare prior to inclusion

78 [22.5–150]

41 [22–93]

Days of RIC/Sham

10 [9,10]

10.5 [10,11]

  1. Continuous variables are described as median and IQR, categorical variables are described as frequencies and percentages.
  2. UC, ulcerative colitis; BMI, body mass index; 5-ASA, 5-aminosalicylic acid; Anti-TNF, antitumor necrosis factor inhibitor; FC, Fecal calprotectin; p-CRP, plasma C-reactive protein; RIC, remote ischemic conditioning.