Figure 2

No difference of change in core body temperature between WT and TRPV1 KO mice upon heat exposure. Abdominal core temperature was measured by a G2 E-mitter telemetry system and plotted at 2-min intervals. Behaviors of mice were monitored by a WiFi camera and the time spent on heat loss behaviors, sleeping and body licking, was manually measured. The ambient temperature was increased from 25.0 to 40.0 °C and maintained at 40.0 °C. WT and TRPV1 KO mice showed almost same increase in core body temperature upon the heat exposure (A). There was no significant difference of sleeping (B) and body licking time (C) between WT and TRPV1 KO mice. Data (n = 5) are expressed as means (± s.e.m.). *p < 0.05 between WT and TRPV1 KO mice (Unpaired Student’s t-test).